Recognises both natural and recombinant human IL-12 p35 + p70
Aufreinigung
Ion exchange chromatography
Sterilität
0.22 μm filtered
Immunogen
Recombinant human IL-12,Myeloma X63/AG.8653 x Balb/c spleen cells
Klon
B-T21
Isotyp
IgG1 kappa
Biological Activity Comment
Inhibits IL-12 induced IFNg synthesis on PHA activated lymphocytes
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
Konservierungsmittel
Without preservative
Lagerung
4 °C
Informationen zur Lagerung
Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
Nagai, Devergne, Mueller, Perkins, van Seventer, van Seventer: "Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation" in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 10, pp. 5233-43, (2003) (PubMed).