Histone 3 Antikörper (pThr11)
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- Target Alle Histone 3 (H3) Antikörper anzeigen
- Histone 3 (H3)
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Bindungsspezifität
- pThr11
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Histone 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- The antibody detects endogenous level of Histone H3 only when phosphorylated at threonine 11.
- Immunogen
- Peptide sequence around phosphorylation site of pThr11 (K-S-T (p) -G-G) derived from Human Histone H3. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Top Product
- Discover our top product H3 Primärantikörper
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- Applikationshinweise
- Western blotting: 1:500-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- Histone 3 (H3)
- Andere Bezeichnung
- Histone H3 (H3 Produkte)
- Synonyme
- H-3 antikoerper, histocompatibility 3 antikoerper, H3 antikoerper
- Hintergrund
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- Molekulargewicht
- 17 kDa
- NCBI Accession
- NP_066403, NP_002098
- UniProt
- P84243
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