RT1.D Antikörper (FITC)

Produktnummer ABIN133247

Produktdetails

Target: RT1.D

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: FITC

Applikation: Flow Cytometry (FACS)

Spezifität: Rat RT1.D (Rat Ia-E)

Aufreinigung: Purified from ascites via Protein G Chromatography

Immunogen: Rat spleen membrane glycoproteins depleted of Ia-A antigens. . Fusion Partner: X63 Ag8.653 . Immunocyte Donor: BALB/c spleen

Klon: OX-17

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.1 mg/ml

Buffer: FITC conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Antigendetails

Target: RT1.D

Hintergrund: Anti-rat RT1.D monoclonal antibody recognizes a monomorphic determinant on the chain of the rat Ia antigen and appears to be the rat homologue of mouse Ia-E. It recognizes the rat Ia product present on B, but not T cells from lymph node or thoracic duct lymph. It does not bind to thymocytes or erythrocytes. The antibody does not cross-react with rat Ia-A or mouse Ia-E antigen, but rabbit antibody raised against the antibody affinity column-purified MRC OX-17 antigen cross-reacted on tissues of mice expressing Ia-E mouse antigen but not on those mouse strains that were Ia-E antigen negative (2).