SERPINB9
Reaktivität: Human
WB, ELISA
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
Western Blot: 2-4 μg/mL. Immunohistochemistry: 20 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
PBS, 0.02 % Thimerosal, 50 % Glycerol, 1 % BSA
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
SERPINB9
(serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
SERPINB9 antikoerper, BB283241 antikoerper, CAP-3 antikoerper, CAP3 antikoerper, PI-9 antikoerper, PI9 antikoerper, Spi6 antikoerper, ovalbumin antikoerper, serpin family B member 9 antikoerper, serpin peptidase inhibitor, clade B (ovalbumin), member 9 antikoerper, serine (or cysteine) peptidase inhibitor, clade B, member 9 antikoerper, Serpinb9 antikoerper, SERPINB9 antikoerper
Hintergrund
Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of serpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme B and of granzyme B-mediated apoptosis, and is also an inhibitor of capase-1 and, to a smaller extent, caspase-4 and caspase-8. PI-9 expression is also upregulated in response to inflammatory stimuli. This upregulation protects cells from apoptosis induced by endogenously expressed or released granzyme B, particulary during target cell killling.Synonyms: CAP-3, CAP3, Cytoplasmic antiproteinase 3, PI-9, PI9, Proteinase inhibitor 9, Serpin B9