DUSP22 Antikörper (N-Term)

Produktnummer ABIN122298

Produktdetails anti-DUSP22 Antikörper

Target: DUSP22 (Dual Specificity Phosphatase 22 (DUSP22))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP22 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects MAP kinase phosphatase X (DUSP22 /SP-1).BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DUSP15 (59 %).

Kreuzreaktivität (Details): Species reactivity (expected):See 'Immunogen Remarks'Species reactivity (tested):Human

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic peptide - KLH conjugated

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry with formalin fixed paraffin embedded tissues: 2-22 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu DUSP22

Target: DUSP22 (Dual Specificity Phosphatase 22 (DUSP22))

Andere Bezeichnung: MAP Kinase Phosphatase X (DUSP22 Produkte)

Synonyme: dusp22 antikoerper, wu:fa11e09 antikoerper, zgc:92816 antikoerper, vhx antikoerper, jkap antikoerper, jsp1 antikoerper, mkpx antikoerper, DUSP22 antikoerper, ch73-170d1.1 antikoerper, zgc:112536 antikoerper, JKAP antikoerper, JSP1 antikoerper, LMWDSP2 antikoerper, MKPX antikoerper, VHX antikoerper, 1110028K04Rik antikoerper, AW212235 antikoerper, dual specificity phosphatase 22 antikoerper, dual specificity phosphatase 22a antikoerper, dual specificity phosphatase 22b antikoerper, DUSP22 antikoerper, dusp22a antikoerper, dusp22 antikoerper, dusp22b antikoerper, Dusp22 antikoerper

Hintergrund: MKPX, also known as JSP-1 for Jnk stimulatory phosphatase-1, belongs to the LMW-DSP subfamily of phosphatases. MKPX has been shown to have the capacity to activate the c-Jun N-terminal kinase (Jnk) signaling pathway. The activation of Jnk has been implicated in a number of important physiological processes, including embryonic morphogenesis, cell survival and apoptosis. At least two mRNA transcripts have been reported. Jnk signaling has been linked to human disease conditions, such as tumor development, cardiac hypertrophy, ischemia/reperfusion injury, diabetes, hyperglycemia-induced apoptosis, and several neurodegenerative disorders. MKPX has been shown to be widely expressed with highest expression in heart, kidney, liver, lung, pancreas and placenta. ESTs have been isolated from a diverse set of human tissues libraries, especially blood and breast. Caution: The acronym MKPX also has been used to describe Dual specificity protein phosphatase 7 (rat).Synonyms: DUSP22, Dual specificity protein phosphatase 22, JNK-stimulatory phosphatase-1, JSP1, MKPX, Mitogen-activated protein kinase phosphatase x

Gen-ID: 100134291

UniProt: Q9NRW4