GRPR Antikörper (2nd Extracellular Domain)

Produktnummer ABIN122256

Produktdetails anti-GRPR Antikörper

Target: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Bindungsspezifität: 2nd Extracellular Domain

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRPR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with Human Gastrin-Releasing Peptide Receptor (GRPR, Family: GPCR, Subfamily: Bombesin), 2nd extracellular domain. GRP-R has been reported in brain, breast, colon, lung, lymph node, ovary, placenta, prostate, stomach, and uterus. It has also been shown to be expressed in several cancers, including those in breast, colon, lung, ovary, pancreas, and prostate.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: GRP-R, GRPR, GRP-preferring bombesin receptor

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide (2nd extracellular domain of human) - KLH conjugated. Remarks: The immunizing peptide shows 83% identity (88% homology) with Mouse andRat.

Anwendungsinformationen

Applikationshinweise: Western blot (5 μg/mL). Immunocytochemistry (Use acetone as fixative). Immunohistochemistry on Paraffin Embedded Sections (4 μg/mL): Steam slides in 0.01 Msodium citrate buffer, pH 6.0 at 99-100 °C for 20 min, Remove from heat and let stand atroom temperature in buffer for 20 min.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or at -20 °C to -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu GRPR

Target: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Andere Bezeichnung: Gastrin-Releasing Peptide Receptor (GRPR Produkte)

Synonyme: GRPR antikoerper, GRP-R antikoerper, gastrin releasing peptide receptor antikoerper, GRPR antikoerper, Grpr antikoerper

Hintergrund: GRPR mediates signals of cellular proliferation and it has been shown to be aberrantly expressed in several cancers such as colon, lung, ovary, pancreas and prostate. It also expressed at very high levels in normal pancreas and at lower levels in brain, breast, colon, lung, lymph node, ovary, placenta, prostate, stomach and uterus.Synonyms: GRP-R, GRP-preferring bombesin receptor, GRPR

Gen-ID: 2925

UniProt: P30550