CD16 Antikörper (FITC)
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- Target Alle CD16 Antikörper anzeigen
- CD16
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD16 Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- The antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcgRIII antigen). The antibody MEM-154 reacts with CD16+ granulocytes.
- Immunogen
- Human granulocytes
- Klon
- MEM-154
- Isotyp
- IgG1
- Top Product
- Discover our top product CD16 Primärantikörper
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- Applikationshinweise
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Flow Cytometry of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade Protease free BSA as a stabilizing agent.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
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Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- CD16
- Andere Bezeichnung
- CD16 (CD16 Produkte)
- Synonyme
- Fcgr3 antikoerper, Fcgr3a antikoerper, CD16 antikoerper, FCGR3 antikoerper, FCGR3@ antikoerper, CD16b antikoerper, FCG3 antikoerper, FCR-10 antikoerper, FCRIII antikoerper, FCRIIIb antikoerper, FcRIII antikoerper, Fc fragment of IgG, low affinity IIa, receptor antikoerper, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antikoerper, Fc fragment of IgG receptor IIIb antikoerper, Fc fragment of IgG receptor IIIa antikoerper, Fc receptor, IgG, low affinity III antikoerper, Fc-gamma RIII antikoerper, Fcgr2a antikoerper, FCGR3A antikoerper, FCGR3B antikoerper, Fcgr3 antikoerper, FCGR3 antikoerper
- Hintergrund
- CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A
- Gen-ID
- 2214
- UniProt
- P08637
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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