Prednisolone Antikörper

Produktnummer ABIN1169577

Produktdetails

Target: Prednisolone

Reaktivität: Hormone

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunoaffinity Chromatography (IAC), Immunoassay (IA)

Sensitivität: 10ng/mL
Prednisolone produces 59% inhibition in a competitive ELISA employing Prednisolone polyclonal Antibody

Produktmerkmale: Polyclonal
High sensitivity
High concentration
Excellent specificity to target compound
Detailed cross reactivity profiles
Available for bulk purchase
Stable when stored at -20 °C
Excellent reproducibility between lot numbers
Matching conjugates available

Immunogen: Prednisolone-BTG

Anwendungsinformationen

Applikationshinweise: The antibody is suitable for the development of immunoassays or immunoaffinity purification columns.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 15.88 mg/mL

Buffer: 20 mM Phosphate, 150 mM Sodium Chloride

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Antigendetails

Target: Prednisolone

Substanzklasse: Hormone

Hintergrund: Dehydroepiandrosterone is the most abundant adrenal androgen in humans and exists predominately in a sulfated form (DHEAS) [1]. DHEA sulfotransferase, known as SULT2A1, converts the androgen precursor DHEA to its inactive sulfate ester, DHEAS. The unconjugated molecules can be converted directly to androgens. Dehydroepiandrosterone is converted to DHEAS in the adrenal glands and liver [2]. DHEA in adults is present at plasma concentrations 100 to 500 times higher than those of testosterone. DHEA can be metabolized to androgens and/or estrogens in the prostate [3]. Hepatic metabolites include 16alpha-hydroxy-DHEA, 7alpha-hydroxy-DHEA, and 7-oxo-DHEA [4]. 7beta-OH-DHEA is a metabolite [5]. The major metabolite produced in humans is a mono-hydroxylated DHEA species [4]. Synthesis of a 7alpha-hydroxy-DHEA and 5-androstene-3beta, 17beta-diol occurs in the frontal cortex, hippocampus, aμgdala, cerebellum and striatum [6].