Kaninchen anti-Human IgG Antikörper

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Antigen
Reaktivität
Human
2896
2761
2297
1676
1453
790
626
454
395
387
359
346
298
296
221
138
135
130
41
31
29
24
16
11
10
8
7
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
Wirt
Kaninchen
6786
4908
1788
923
609
392
91
68
55
18
8
5
5
5
2
1
1
Klonalität
Polyklonal
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen IgG isolated from a pool of normal Human sera.
Reinigung Purified
Hintergrund IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75 % of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66 %), IgG2 (23 %), IgG3 (7 %) and IgG4 (4 %).Synonyms: Human Immunoglobulin G
Applikationshinweise Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: Use at1/200-1/500 dilution in an ABC method (30 minutes at room temperature). Proteolytic treatment is required prior to immunostaining of formalin fixed paraffinembedded tissue sections. Recommended Positive Control: Tonsil

Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 18.9 mg/mL
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
Bilder des Herstellers
Immunohistochemistry (IHC) image for Rabbit anti-Human IgG antibody (ABIN115322) Formalin fixed paraffin embedded human tonsil stained with IgG antibody. ABIN115322
Allgemeine Veröffentlichungen Koslov, Maupin, Pradhan, Morrow, Rimm: "Alpha-catenin can form asymmetric homodimeric complexes and/or heterodimeric complexes with beta-catenin." in: The Journal of biological chemistry, Vol. 272, Issue 43, pp. 27301-6, 1997 (PubMed).