Iba1 Antikörper (Biotin)

Produktnummer ABIN112010

Produktdetails anti-Iba1 Antikörper (Biotin)

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Iba1 Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Recognizes AIF-1. This antibody BM4114B reacts with activated Macrophages / Microglial cells.

Aufreinigung: Affinity Chromatography.

Immunogen: Purified Human recombinant AIF-1 Epitope is not further characterized.

Klon: 1022-5

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections: 5 μg/mL (1/40). Pretreatment is not necessary. Suggested Positive Control: Human spleen. This antibody does not react on routinely processed Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore by adding 0.5 mL distilled water.

Konzentration: 0.2 mg/mL

Buffer: PBS containing 5 mg/mL BSA as a stabilizer and 0.09 % Sodium Azide as a preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted Prior to and following reconstitution at 2-8 °C. DO NOT FREEZE!

Details zu Iba1

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Andere Bezeichnung: AIF1 (IBA1 Produkte)

Synonyme: AIF-1 antikoerper, IBA1 antikoerper, IRT-1 antikoerper, IRT1 antikoerper, AI607846 antikoerper, D17H6S50E antikoerper, G1 antikoerper, Iba1 antikoerper, Bart1 antikoerper, iba1 antikoerper, mrf-1 antikoerper, fa04b11 antikoerper, wu:fa04b11 antikoerper, AIF antikoerper, AIF1 antikoerper, aif1 antikoerper, allograft inflammatory factor 1 antikoerper, AIF1 antikoerper, Aif1 antikoerper, aif1 antikoerper

Hintergrund: Allograft Inflammatory Factor-1 is a Ca2+-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated with chronic inflammatory processes. AIF-1, like the Ca2+-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.Synonyms: AIF-1, Allograft inflammatory factor 1, IBA1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1

Gen-ID: 199

NCBI Accession: NP_001614

UniProt: P55008

Pathways: Smooth Muscle Cell Migration