Western Blot (1:100-500), Immunohistochemistry, IHC (1:100-500), Immunocytochemistry, ICC (1:100-500). Other applications have not been tested. The optimal dilutions should be determined by end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
Konservierungsmittel
Sodium azide, Thimerosal (Merthiolate)
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Haltbarkeit
12 months
Target
BMPR2
(Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
Andere Bezeichnung
Bone morphogenetic protein receptor type II, BMPR2 (BMPR2 Produkte)
Synonyme
BMPR-II antikoerper, BMPR3 antikoerper, BMR2 antikoerper, BRK-3 antikoerper, PPH1 antikoerper, T-ALK antikoerper, 2610024H22Rik antikoerper, AL117858 antikoerper, AW546137 antikoerper, BB189135 antikoerper, BMP-2 antikoerper, BMPR-2 antikoerper, BMPRII antikoerper, Gm20272 antikoerper, Bmpr-II antikoerper, bmprii antikoerper, bone morphogenetic protein receptor type 2 antikoerper, bone morphogenetic protein receptor, type II b (serine/threonine kinase) antikoerper, bone morphogenetic protein receptor, type II (serine/threonine kinase) antikoerper, BMPR2 antikoerper, bmpr2b antikoerper, Bmpr2 antikoerper
Hintergrund
Bone morphogenetic protein receptor type II, BMPR2 is a serine/threonine receptor kinase. It binds bone morphogenetic proteins, members of the TGF beta superfamily of ligands. BMPs are involved in a host of cellular functions including osteogenesis, cell growth and cell differentiation. Unlike the TGF beta type II receptor, which has a high affinity for TGF- beta1, BMPR2 does not have a high affinity for BMP-2, BMP-7 and BMP-4, unless it is co-expressed with a type I BMP receptor. 1 The low affinity for ligands suggests that BMPR2 may differ in the from other type II TGF beta receptors in that the ligand may bind the type I receptor first. 2