XAGE1 Antikörper (C-Term, Isoform 1d)

Produktnummer ABIN1109518

Produktdetails anti-XAGE1 Antikörper

Target: XAGE1 (XAGE1A) (X Antigen Family, Member 1A (XAGE1A))

Bindungsspezifität: C-Term, Isoform 1d

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser XAGE1 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: CGFGFRRQGE DNT

Spezifität: This antibody is expected to recognise Isoform d (NP_597673.1) only. Reported variants represent identical protein (NP_597673.1, NP_001091067.1, NP_001091074.1, NP_001091062.1, NP_001091065.1).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide with sequence from the C-Terminus of Human XAGE1D / GAGED2 (NP_597673.1). Genename: GAGED2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu XAGE1

Target: XAGE1 (XAGE1A) (X Antigen Family, Member 1A (XAGE1A))

Andere Bezeichnung: XAGE-1 / G Antigen Family D Member 2 (XAGE1A Produkte)

Hintergrund: XAGE1 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. XAGE1 is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. XAGE1 contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of XAGE1 generates 3 transcript variants, and one of which includes 2 transcripts generated from alternate transcription initiation sites.Synonyms: CT12.1, Cancer/testis antigen 12.1, GAGED2, XAGE1, XAGE1A, XAGE1B, XAGE1C, XAGE1D, XAGE1E

Gen-ID: 653048

NCBI Accession: NP_001091061