TRAFD1 Antikörper (C-Term)

Produktnummer ABIN1109296

Produktdetails anti-TRAFD1 Antikörper

Target: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAFD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: TATNHVTEGI PRLDSQPQET SPELPRRRVR HQGDLSSGYL DDTKQETANG

Kreuzreaktivität (Details): Species reactivity (expected):Rat, Mouse, Dog, BovineSpecies reactivity (tested):Human

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-TRAFD1 antibody: synthetic peptide directed towards the C terminal of human TRAFD1.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu TRAFD1

Target: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Andere Bezeichnung: TRAFD1 / FLN29 (TRAFD1 Produkte)

Synonyme: MGC80116 antikoerper, fln29 antikoerper, MGC89491 antikoerper, TRAFD1 antikoerper, 1110008K06Rik antikoerper, Fln29 antikoerper, FLN29 antikoerper, TRAF-type zinc finger domain containing 1 antikoerper, TRAF-type zinc finger domain containing 1 L homeolog antikoerper, TRAF-type zinc finger domain-containing protein 1 antikoerper, TRAF type zinc finger domain containing 1 antikoerper, TRAFD1 antikoerper, trafd1.L antikoerper, trafd1 antikoerper, trad1 antikoerper, Trafd1 antikoerper

Hintergrund: TRAFD1 is a negative feedback regulator that controls excessive innate immune responses. It regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways and may inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. TRAFD1 may negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.Synonyms: TRAF-type zinc finger domain-containing protein 1

Gen-ID: 10906

NCBI Accession: NP_006691