TLE3 Antikörper (N-Term)

Produktnummer ABIN1109265

Produktdetails anti-TLE3 Antikörper

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLE3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GSSSGLLALG ALGSQAHLTV KDEKNHHELD HRERESSANN SVSPSESLRA

Kreuzreaktivität (Details): Species reactivity (expected):Dog, Mouse, Rat, ZebrafishSpecies reactivity (tested):Human

Aufreinigung: Purified using Protein A affinity column

Immunogen: The immunogen for anti-TLE3 antibody: synthetic peptide directed towards the N terminal of human TLE3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu TLE3

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Andere Bezeichnung: TLE3 (TLE3 Produkte)

Synonyme: TLE3 antikoerper, ESG antikoerper, ESG1 antikoerper, Xesg1 antikoerper, esg2 antikoerper, esg3 antikoerper, grg2 antikoerper, grg3 antikoerper, hst18976 antikoerper, tle3 antikoerper, xgrg3 antikoerper, ESG3 antikoerper, GRG3 antikoerper, HsT18976 antikoerper, Esp3 antikoerper, 2610103N05Rik antikoerper, Grg3a antikoerper, Grg3b antikoerper, mKIAA1547 antikoerper, transducin like enhancer of split 3 antikoerper, transducin like enhancer of split 2 antikoerper, transducin-like enhancer of split 3 antikoerper, TLE3 antikoerper, tle2 antikoerper, Tle3 antikoerper

Hintergrund: The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.TLE3 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.Synonyms: ESG3, GRG3, KIAA1547, Transducin-like enhancer protein 3

Gen-ID: 7090

NCBI Accession: NP_005069

Pathways: SARS-CoV-2 Protein Interaktom