TIMP3 Antikörper (C-Term)

Produktnummer ABIN1109258

Produktdetails anti-TIMP3 Antikörper

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects TIMP3 (C-term). No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Immunogen affinity purified

Immunogen: A peptide mapping at the C-terminal end of TIMP-3 of human origin .Remarks: Sequence is different to the related rat sequence by single amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TIMP3

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Andere Bezeichnung: TIMP3 (TIMP3 Produkte)

Synonyme: TIMP-3 antikoerper, TIMP3 antikoerper, timp3 antikoerper, HSMRK222 antikoerper, K222 antikoerper, K222TA2 antikoerper, SFD antikoerper, IMP-3 antikoerper, timp3-A antikoerper, Timp-3 antikoerper, metalloproteinase inhibitor 3 antikoerper, TIMP metallopeptidase inhibitor 3 antikoerper, Metalloproteinase inhibitor 3 antikoerper, TIMP metallopeptidase inhibitor 3 L homeolog antikoerper, tissue inhibitor of metalloproteinase 3 antikoerper, CpipJ_CPIJ003282 antikoerper, TIMP3 antikoerper, timp3 antikoerper, Timp3 antikoerper, timp3.L antikoerper

Hintergrund: The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).Synonyms: Metalloproteinase inhibitor 3, Protein MIG-5, TIMP-3, Tissue inhibitor of metalloproteinases 3

Gen-ID: 7078

NCBI Accession: NP_000353

UniProt: P35625