SLC25A19
Reaktivität: Human, Maus
WB, ELISA
Wirt: Kaninchen
Polyclonal
PE
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Add 50 μL of distilled water to a final concentration of 1 mg/mL.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
Target
SLC25A19
(Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 (SLC25A19))
zgc:111878 antikoerper, 2900089E13Rik antikoerper, DNC antikoerper, MUP1 antikoerper, TPC antikoerper, MCPHA antikoerper, THMD3 antikoerper, THMD4 antikoerper, solute carrier family 25 member 19 antikoerper, solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 antikoerper, Slc25a19 antikoerper, slc25a19 antikoerper, SLC25A19 antikoerper
Hintergrund
This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.Synonyms: DNC, MUP1, Mitochondrial thiamine pyrophosphate carrier, Mitochondrial uncoupling protein 1, Solute carrier family 25 member 19