RRAD Antikörper (Internal Region)

Produktnummer ABIN1108906

Produktdetails anti-RRAD Antikörper

Target: RRAD (Ras-Related Associated with Diabetes (RRAD))

Bindungsspezifität: AA 36-48, Internal Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser RRAD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes RRAD (36-48).

Kreuzreaktivität (Details): Species reactivity (expected):Human, Rat, Canine (Dog), Porcine, Bovine.
Species reactivity (tested):Mouse.

Aufreinigung: Affinity Chromatography

Immunogen: Peptide with sequence (C-HRRSMPVDERDLQ) from the internal region of Human RRAD (NP_004156.1). Genename: RRAD Remarks: Reported variants represent identical protein: NP_004156.1, NP_001122322.1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RRAD

Target: RRAD (Ras-Related Associated with Diabetes (RRAD))

Andere Bezeichnung: RRAD / RAD (RRAD Produkte)

Synonyme: ZGC:63471 antikoerper, RRAD antikoerper, RAD antikoerper, RAD1 antikoerper, REM3 antikoerper, Rad antikoerper, RRAD, Ras related glycolysis inhibitor and calcium channel regulator antikoerper, Ras-related associated with diabetes antikoerper, RRAD antikoerper, Rrad antikoerper

Hintergrund: May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D. Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.Synonyms: GTP-binding protein RAD, RAD1, Ras associated with diabetes

Molekulargewicht: 33.2 kDa (Mouse NP_062636.2 and Human NP_004156.1).

Gen-ID: 6236

NCBI Accession: NP_001122322