RAG1 Antikörper (C-Term)

Produktnummer ABIN1108824

Produktdetails anti-RAG1 Antikörper

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Bindungsspezifität: C-Term

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IIERDGSIGA WASEGNESGN KLFRRFRKMN ARQSKCYEME DVLKHHWLYT

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse.

Aufreinigung: Immunoaffinity column

Immunogen: Synthetic peptide corresponding to a near C-terminal region of mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu RAG1

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Andere Bezeichnung: RAG1 / RNF74 (RAG1 Produkte)

Synonyme: RAG-1 antikoerper, rag1 antikoerper, RNF74 antikoerper, Rag-1 antikoerper, rag-1 antikoerper, rag1a antikoerper, recombination activating 1 antikoerper, recombination activating gene 1 antikoerper, recombination activating gene 1 S homeolog antikoerper, Rag1 antikoerper, RAG1 antikoerper, rag1 antikoerper, rag1.S antikoerper

Hintergrund: As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities.Synonyms: RAG-1, RING finger protein 74, V(D)J recombination-activating protein 1

Molekulargewicht: RAG1: 119 kDa

Gen-ID: 19373

NCBI Accession: NM_009019