Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
Spezifität
This antibody is directed to the common part of these proteins (PTPBR7, PTP-SL and PTPPBSγ). Specificity has been tested in Immunoprecipitation, Immunohistochemistry and Immunoblotting. Crossreacts with the striatum enriched phosphatase (STEP) when using antibody in Immunoblotting (Figure 1). Additional tests for cross reactivity have not yet been performed.
Kreuzreaktivität (Details)
Species reactivity (tested):Mouse.
Aufreinigung
Protein A Chromatography
Immunogen
Recombinant PTP-SL-GST (NCBI accession number BN000437, expression vector pGEX-2T), expressed in E.coli.
EC-PTP antikoerper, PCPTP1 antikoerper, PTP-SL antikoerper, PTPBR7 antikoerper, PTPRQ antikoerper, Pcptp1 antikoerper, ec-ptp antikoerper, pcptp1 antikoerper, ptp-sl antikoerper, ptpbr7 antikoerper, PTPRR antikoerper, Gmcp1 antikoerper, RPTPRR antikoerper, mPTP213 antikoerper, protein tyrosine phosphatase, receptor type R antikoerper, protein tyrosine phosphatase, receptor type, R antikoerper, protein tyrosine phosphatase, receptor type R L homeolog antikoerper, protein tyrosine phosphatase, receptor type, r antikoerper, receptor-type tyrosine-protein phosphatase R antikoerper, PTPRR antikoerper, Ptprr antikoerper, ptprr.L antikoerper, ptprr antikoerper, LOC100715069 antikoerper
Hintergrund
Protein tyrosine phosphatases (PTPs) are the enzymes that are instrumental in determining the spatial and temporal balance between the tyrosine phosphorylated and non-phosphorylated targets, and thus coordinately regulate these cellular responses to extracellular cues. The Ptprr gene gives rise to 4 different neuronal phosphatases which differ in length of their N-terminal part and subcellular localization. PTPBR7 (72 kDa) is receptor-like, PTP-SL (60 kDa) is membrane associated and PTPPBSγ (42 and 37 kDa) is a cytosolic phoaphatase.Synonyms: Ch-1PTPase, ECPTP, NC-PTPCOM1, PCPTP1, PTPRQ, Protein-tyrosine phosphatase PCPTP1, R-PTP-R, Receptor-type tyrosine-protein phosphatase R