Paired Box 3 Antikörper (Internal Region)

Produktnummer ABIN1108590

Produktdetails anti-Paired Box 3 Antikörper

Target: Paired Box 3 (PAX3)

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Paired Box 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody is expected to recognize isoforms PAX3 (NP_852122.1), PAX3d (NP_852123.1), PAX3e (NP_852124.1), PAX3g (NP_852126.1), PAX3h (NP_852125.1) and PAX3i (NP_001120838.1).

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog), Bovine, Porcine.
Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity Chromatography

Immunogen: Peptide with sequence C-STVHQSTIPSNPD, from the internal region of the protein sequence according to NP_852122.1, NP_000429.2, NP_039230.1, NP_852123.1, NP_852124.1, NP_852126.1, NP_852125.1, NP_001120838.1. Genename: PAX3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Paired Box 3

Target: Paired Box 3 (PAX3)

Andere Bezeichnung: PAX3 (PAX3 Produkte)

Synonyme: PAX3 antikoerper, cdhs antikoerper, hup2 antikoerper, pax-3 antikoerper, ws1 antikoerper, xpax3 antikoerper, Pax3 antikoerper, pax3 antikoerper, pax3b antikoerper, xPax3-B antikoerper, CDHS antikoerper, HUP2 antikoerper, WS1 antikoerper, WS3 antikoerper, Pax-3 antikoerper, Sp antikoerper, splotch antikoerper, zgc:92547 antikoerper, paired box 3 antikoerper, paired box 3 L homeolog antikoerper, paired box 3a antikoerper, PAX3 antikoerper, pax3 antikoerper, pax3.L antikoerper, Pax3 antikoerper, pax3a antikoerper

Hintergrund: This protein is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.Synonyms: HUP2, Paired box protein Pax-3, Pax-3

Molekulargewicht: 53.0 kDa (Human NP_852122.1) and 52.9 kDa (Mouse NP_032807.3)

Gen-ID: 5077

NCBI Accession: NP_000429

Pathways: Sensory Perception of Sound, Tube Formation