PAWR Antikörper
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- Target Alle PAWR Antikörper anzeigen
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAWR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Reacts with Human 36 kDa Par-4 protein.
- Aufreinigung
- Affinity Chromatography on Protein A
- Immunogen
- Synthetic peptide derived from internal domain of Human Par-4.
- Top Product
- Discover our top product PAWR Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore in distilled water.
- Buffer
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
- Andere Bezeichnung
- PAR4 / PAWR (PAWR Produkte)
- Synonyme
- MGC81382 antikoerper, pawrl antikoerper, zgc:103513 antikoerper, PAWR antikoerper, PAR4 antikoerper, Par-4 antikoerper, Par4 antikoerper, 2310001G03Rik antikoerper, pro-apoptotic WT1 regulator antikoerper, PRKC, apoptosis, WT1, regulator L homeolog antikoerper, PRKC, apoptosis, WT1, regulator antikoerper, PAWR antikoerper, pawr.L antikoerper, pawr antikoerper, Pawr antikoerper
- Hintergrund
- Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.Synonyms: PRKC apoptosis WT1 regulator protein, Par-4, Prostate apoptosis response 4 protein
- Gen-ID
- 5074
- NCBI Accession
- NP_002574
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