HCRTR1 Antikörper (C-Term)

Produktnummer ABIN1108529

Produktdetails anti-HCRTR1 Antikörper

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCRTR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects Orexin Receptor 1+2 (C-term). No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat.

Aufreinigung: Immunogen affinity purified

Immunogen: Synthetic peptide corresponding to a sequence at the C-terminal of human Orexin Receptor .Remarks: Sequence is identical to the related mouse and rat sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu HCRTR1

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Andere Bezeichnung: Orexin Receptor Type 1 (HCRTR1 Produkte)

Synonyme: OX1R antikoerper, Ox1r antikoerper, Hctr1 antikoerper, HCRTR1 antikoerper, hypocretin receptor 1 antikoerper, hypocretin (orexin) receptor 1 antikoerper, HCRTR1 antikoerper, Hcrtr1 antikoerper

Hintergrund: Orexins are endogeneous peptides that activate Orexin Receptor type 1 and type 2, two closely related G-protein coupled receptors. Orexins-A and -B are hypothalamic peptides derived from a precursor called preproorexin and affect the stimulation of food intake. They act on G protein receptors named orexin receptor-1 (OX1R) and orexin receptor-2 (OX2R), respectively.Stimulation of these receptors by orexins causes an increase in intracellular calcium levels in hypothalamic cells in vitro. In vivo, orexins control feeding and may also be involved in modulating sleep-wake cycles and other hypothalamic functions.Synonyms: HCRTR1, HCRTR2, Ox1r, Ox2r

Gen-ID: 3061

NCBI Accession: NP_001516

UniProt: O43613

Pathways: Feeding Behaviour