NFE2L3 Antikörper (Middle Region)

Produktnummer ABIN1108444

Produktdetails anti-NFE2L3 Antikörper

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Rind (Kuh), Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFE2L3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NPEQTLPGTN LTGFLSPVDN HMRNLTSQDL LYDLDINIFD EINLMSLATE

Kreuzreaktivität (Details): Species reactivity (expected):Mouse (92 %), Dog (92 %), Bovine (85 %), Rabbit (92 %).
Species reactivity (tested):Human.

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-NFE2L3 antibody: synthetic peptide directed towards the middle region of human NFE2L3.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu NFE2L3

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Andere Bezeichnung: NFE2L3 (NFE2L3 Produkte)

Synonyme: NRF3 antikoerper, Nrf3 antikoerper, nuclear factor, erythroid 2 like 3 antikoerper, nuclear factor, erythroid derived 2, like 3 antikoerper, nuclear factor, erythroid 2-like 3 antikoerper, NFE2L3 antikoerper, Nfe2l3 antikoerper

Hintergrund: NFE2L3 belongs to the bZIP family, CNC subfamily, and activates erythroid-specific, globin gene expression. It forms heterodimers with MAFG, MAFK and other small MAF proteins that binds to the MAF recognition elements (MARE). NFE2L3 also called NRF3 is highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression is observed in heart, brain, lung, skeletal muscle, kidney and pancreas.Synonyms: NF-E2-related factor 3, NFE2-related factor 3, NRF3, Nuclear factor erythroid 2-related factor 3

Molekulargewicht: 76 kDa (694 amino acids)

Gen-ID: 9603

NCBI Accession: NP_004280