KCND3 Antikörper (N-Term)

Produktnummer ABIN1107930

Produktdetails anti-KCND3 Antikörper

Target: KCND3 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCND3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody reacts with 73 kDa KCND3 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from N-term domain of KCND3 protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Prior to reconstitution store at-20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu KCND3

Target: KCND3 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3))

Andere Bezeichnung: KCND3 (KCND3 Produkte)

Synonyme: KCND3 antikoerper, zgc:55306 antikoerper, wu:fi06g01 antikoerper, kv4.3 antikoerper, K(v)4.3 antikoerper, AW045978 antikoerper, Kncd3 antikoerper, Kv4.3 antikoerper, KCND3L antikoerper, KCND3S antikoerper, KSHIVB antikoerper, KV4.3 antikoerper, kcnd3-A antikoerper, xKv4.3 antikoerper, potassium voltage-gated channel subfamily D member 3 antikoerper, potassium voltage-gated channel, Shal-related subfamily, member 3 antikoerper, potassium channel, voltage gated Shal related subfamily D, member 3 antikoerper, potassium voltage-gated channel, Shal-related family, member 3 antikoerper, potassium channel, voltage gated Shal related subfamily D, member 3 L homeolog antikoerper, KCND3 antikoerper, kcnd3 antikoerper, Kcnd3 antikoerper, kcnd3.L antikoerper

Hintergrund: Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligand- gated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels. Potassium volgate-gated channel subfamily D member 3 (also knowns as Kv4.3) is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current, the main contributing current to the repolarizing phase 1 of the cardiac action potential.Synonyms: Potassium voltage-gated channel subfamily D member 3, Voltage-gated potassium channel subunit Kv4.3

Gen-ID: 3752

NCBI Accession: NP_004971

UniProt: Q9UK17