KATNA1 Antikörper (C-Term)

Produktnummer ABIN1107914

Produktdetails anti-KATNA1 Antikörper

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KATNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR

Kreuzreaktivität (Details): Species reactivity (tested):Mouse, human.

Aufreinigung: Immunoaffinity column

Immunogen: Synthetic peptide directed towards the C-terminal region of mouse Katna1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu KATNA1

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Andere Bezeichnung: KATNA1 (KATNA1 Produkte)

Synonyme: si:dkey-15j16.1 antikoerper, zgc:110580 antikoerper, katna1 antikoerper, katanin catalytic subunit A1 antikoerper, katanin p60 (ATPase containing) subunit A 1 antikoerper, katanin p60 (ATPase-containing) subunit A1 antikoerper, KATNA1 antikoerper, katna1 antikoerper, Katna1 antikoerper

Hintergrund: Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth.Synonyms: Katanin p60 ATPase-containing subunit A1, Katanin p60 subunit A1, p60 katanin

Molekulargewicht: Katna1: 54 kDa

Gen-ID: 23924

NCBI Accession: NM_011835

Pathways: Microtubule Dynamics