JUP Antikörper
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- Target Alle JUP Antikörper anzeigen
- JUP (Junction Plakoglobin (JUP))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser JUP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Spezifität
- The antibody detects Plakoglobin.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, rat. Weakly with mouse.
- Aufreinigung
- Protein G
- Klon
- 15F11
- Isotyp
- IgG1
- Top Product
- Discover our top product JUP Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- JUP (Junction Plakoglobin (JUP))
- Andere Bezeichnung
- Junction Plakoglobin (JUP Produkte)
- Synonyme
- ARVD12 antikoerper, CTNNG antikoerper, DP3 antikoerper, DPIII antikoerper, PDGB antikoerper, PKGB antikoerper, arvd12 antikoerper, ctnng antikoerper, dp3 antikoerper, dpiii antikoerper, pdgb antikoerper, pkgb antikoerper, plak antikoerper, D930025P04Rik antikoerper, PG antikoerper, cb80 antikoerper, danPG antikoerper, fb11b06 antikoerper, jup antikoerper, wu:fb11b06 antikoerper, junction plakoglobin antikoerper, junction plakoglobin L homeolog antikoerper, Junction plakoglobin antikoerper, junction plakoglobin a antikoerper, junction plakoglobin S homeolog antikoerper, JUP antikoerper, Jup antikoerper, jup antikoerper, jup.L antikoerper, Tsp_06656 antikoerper, plak antikoerper, jupa antikoerper, jup.S antikoerper
- Hintergrund
- Plakoglobin, also known as gamma-catenin belongs together with alpha- and beta catenin to the catenin family. Catenins mediates cell-cell adhesion by interaction with cadherins. Plakoglobin is found in desmosomes and adherens junctions. Plakoglobin is highly homologous to beta-catenin although its function differs from that of beta-catenin. Whereas beta-catenin has been found in potentiating hyperproliferation and tumor formation, plakoglobin can suppress tumorigenicity. Overexpression of plakoglobin has been shown to suppress cell proliferation and cell tumorigenicity in animals. Furthermore reduced plakoglobin expression has been found in tumor tissues and metastatic lesions of renal cells, esophageal carcinomas and in skin carcinomas.Synonyms: CTNNG, Catenin gamma, DP3, Desmoplakin III, Desmoplakin-3, JUP
- Gen-ID
- 3728
- Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location
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