JUP Antikörper
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- Target Alle JUP Antikörper anzeigen
- JUP (Junction Plakoglobin (JUP))
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Reaktivität
- Human, Ratte, Huhn
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser JUP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Recognizes Catenin Gamma (Plakoglobin). No cross reactivity with other proteins.
- Aufreinigung
- Affinity Chromatography
- Immunogen
- Recombinant Chicken plakoglobin.
- Klon
- CN-3
- Isotyp
- IgG1
- Top Product
- Discover our top product JUP Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore with 1.2 % Sodium Acetate or neutral PBS.
- Konzentration
- 0.1 mg/mL
- Buffer
- 1.2 % Sodium Acetate containing 2 mg BSA and 0.01 mg Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- JUP (Junction Plakoglobin (JUP))
- Andere Bezeichnung
- Junction Plakoglobin (JUP Produkte)
- Synonyme
- ARVD12 antikoerper, CTNNG antikoerper, DP3 antikoerper, DPIII antikoerper, PDGB antikoerper, PKGB antikoerper, arvd12 antikoerper, ctnng antikoerper, dp3 antikoerper, dpiii antikoerper, pdgb antikoerper, pkgb antikoerper, plak antikoerper, D930025P04Rik antikoerper, PG antikoerper, cb80 antikoerper, danPG antikoerper, fb11b06 antikoerper, jup antikoerper, wu:fb11b06 antikoerper, junction plakoglobin antikoerper, junction plakoglobin L homeolog antikoerper, Junction plakoglobin antikoerper, junction plakoglobin a antikoerper, junction plakoglobin S homeolog antikoerper, JUP antikoerper, Jup antikoerper, jup antikoerper, jup.L antikoerper, Tsp_06656 antikoerper, plak antikoerper, jupa antikoerper, jup.S antikoerper
- Hintergrund
- Junction Plakoglobin (JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.Synonyms: CTNNG, Catenin gamma, DP3, Desmoplakin III, Desmoplakin-3, JUP
- Gen-ID
- 3728
- NCBI Accession
- NP_002221
- UniProt
- P14923
- Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location
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