GNRHR Antikörper (Extracellular Domain, N-Term)

Produktnummer ABIN1107412

Produktdetails anti-GNRHR Antikörper

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Bindungsspezifität: AA 1-29, Extracellular Domain, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GNRHR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Sequenz: MANSASPEQN QHCSAINNSI PLMQGNLPY

Spezifität: This Monoclonal antibody A9E4 reacts with GnRH receptors in the anterior pituitary. A9E4 showed specificity for the synthetic peptide in ELISA and Dot blot, it has a higher affinity for the antigen than the GnRH receptor antibody clone F1G4 (Cat.-No. AM32064PU-N). A9E4 specifically stains human GnRH receptors on frozen tissue of the anterior pituitary. Recognition was supported by Western blotting.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to the amino acids 1-29 of the Human GnRH receptor extracellular domain conjugated to BSA. Splenocytes were fused with SP2/0 mouse myeloma cells. Stability was established by subcloning four times.

Klon: A9E4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C

Details zu GNRHR

Target: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Andere Bezeichnung: GnRH Receptor / GNRHR (GNRHR Produkte)

Synonyme: GNRHR1 antikoerper, GRHR antikoerper, HH7 antikoerper, LHRHR antikoerper, LRHR antikoerper, GNRHR antikoerper, GH1 antikoerper, Lhrhr antikoerper, GNRHR1/III antikoerper, GNRHR2 antikoerper, xgnrhr antikoerper, gnrhr3/ii antikoerper, gnrh-r antikoerper, gonadotropin releasing hormone receptor antikoerper, gonadotropin-releasing hormone receptor antikoerper, GNRHR antikoerper, Gnrhr antikoerper, gnrhr antikoerper, gnrh-r antikoerper

Hintergrund: Gonadotropin releasing hormone (GnRH) receptor is a protein of 54-60 kDa. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulated hormone (FSH). The receptor contains of seven hydrophobic transmembrane domains connected by hydrophillic extracellular, and intracellular loops characteristic of G-protein coupled receptors.Synonyms: GRHR, GnRH-R, Gonadotropin-releasing hormone receptor

Gen-ID: 2798

NCBI Accession: NP_000397

UniProt: P30968