Dopamine Receptor d1 Antikörper (C-Term)

Produktnummer ABIN1107009

Produktdetails anti-Dopamine Receptor d1 Antikörper

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dopamine Receptor d1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects Dopamine D1 Receptor at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human DRD1 .Remarks: Sequence is identical to the related rat and mouse sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu Dopamine Receptor d1

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Andere Bezeichnung: Dopamine D1 Receptor (DRD1 Produkte)

Synonyme: DRD1 antikoerper, Dop1 antikoerper, D1A antikoerper, DADR antikoerper, DRD1A antikoerper, drd1 antikoerper, C030036C15Rik antikoerper, Drd-1 antikoerper, Drd1 antikoerper, Gpcr15 antikoerper, D1a antikoerper, Drd1a antikoerper, dopamine receptor D1 antikoerper, dopamine receptor, D1 antikoerper, dopamine receptor D1b antikoerper, DRD1 antikoerper, Dop1 antikoerper, drd1b antikoerper, Drd1 antikoerper

Hintergrund: Dopamine receptor D1, also known as DRD1, is a human gene. It is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guaninenucleotide-binding) proteins. D2 receptors inhibit adenylyl cyclase, but D1 receptors stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. Dopamine D1 and D2 receptors are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1 receptors regulate neuron growth and differentiation, influence behaviour and modify dopamine D2 receptor-mediated events. And the presence of a D1 receptor gene restriction fragment length polymorphism will be helpful for future disease linkage studies. DRD1 also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.Synonyms: D(1A) dopamine receptor, DRD1

Gen-ID: 1812

NCBI Accession: NP_000785

UniProt: P21728

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity