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Desmoglein 1 Antikörper

DSG1 Reaktivität: Human WB, IF, IP, IHC (fro) Wirt: Maus Monoclonal 27B2 unconjugated
Produktnummer ABIN1106981
  • Target Alle Desmoglein 1 (DSG1) Antikörper anzeigen
    Desmoglein 1 (DSG1)
    Reaktivität
    • 86
    • 23
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 56
    • 30
    • 1
    Maus
    Klonalität
    • 51
    • 36
    Monoklonal
    Konjugat
    • 38
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser Desmoglein 1 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 27
    • 27
    • 21
    • 20
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    The monoclonal antibody 27B2 reacts with the 165 kDa desmoglein 1 protein. Furthermore it is not cross reactive with desmoglein 2 or desmoglein 3.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Protein G
    Klon
    27B2
    Isotyp
    IgG1
    Top Product
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C.
  • Target
    Desmoglein 1 (DSG1)
    Andere Bezeichnung
    Desmoglein-1 (DSG1 Produkte)
    Synonyme
    CDHF4 antikoerper, DG1 antikoerper, DSG antikoerper, PPKS1 antikoerper, SPPK1 antikoerper, DSG-1 antikoerper, DSG1 antikoerper, Dsg1b antikoerper, Dsg1c antikoerper, desmoglein 1 antikoerper, desmoglein 4 antikoerper, DSG1 antikoerper, DSG4 antikoerper, Dsg1 antikoerper
    Hintergrund
    Desmoglein 1 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.Synonyms: CDHF4, Cadherin family member 4, DG1, DGI, DSG1, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen
    Gen-ID
    1828
    NCBI Accession
    NP_001933
    UniProt
    Q02413
    Pathways
    Cell-Cell Junction Organization
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