CD1b Antikörper

Produktnummer ABIN1106010

Produktdetails anti-CD1b Antikörper

Target: CD1b (CD1B)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD1b Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: 100-1A5 binds with CD1b which is a 45 kDa membrane glycoprotein expressed together with beta-2 Microglobulin. This antibody reacts with cortical thymocytes, Langerhans cells interdigitating cells and with pyramidal cells in the brain. It can be applied for characterization of leukemia's and lymphomas.
Cellular Localization: Cell membrane and cytoplasm.

Aufreinigung: Purified

Klon: 100-1A5

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CD1b

Target: CD1b (CD1B)

Andere Bezeichnung: CD1b (CD1B Produkte)

Synonyme: CD1 antikoerper, CD1A antikoerper, R1 antikoerper, CD1B3 antikoerper, CD1B antikoerper, CD1-b antikoerper, CD1b molecule antikoerper, T-cell surface glycoprotein CD1b-3 antikoerper, CD1b1 molecule antikoerper, T-cell surface glycoprotein CD1b1 antikoerper, CD1B antikoerper, LOC443423 antikoerper, CD1B1 antikoerper, LOC100720602 antikoerper

Hintergrund: CD1b which is associated with β2 microglobulin (1) is expressed on cortical thymocytes (moderate), Langerhans cells, interdigitating cells and brain pyramidal cells (1). It is up-regulated in peripheral neuropathy and inflammatory diseases (2,3). CD1b is the member of CD1 family. At least five CD1 genes (CD1a, b, c, d, and e) are identified (1). Unlike other members in CD1 family which have multiple splicing patterns, CD1b only revealed a single membrane RNA product (1). CD1 proteins including CD1b have been demonstrated to restrict T-cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation (4)Synonyms: T-cell surface glycoprotein CD1b

Molekulargewicht: 45 kDa

Gen-ID: 910