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CXCR2 Antikörper (Middle Region)
CXCR2
Reaktivität: Human
WB, IP, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1105962
Produktdetails anti-CXCR2 Antikörper
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Target
Alle CXCR2 Antikörper anzeigen
CXCR2
(Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
Bindungsspezifität
Alle Epitope für CXCR2 Antikörper
Middle Region
Reaktivität
Alle Reaktivitäten für CXCR2 Antikörper
Human
Wirt
Alle Wirte für CXCR2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für CXCR2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für CXCR2 Antikörper
Dieser CXCR2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CXCR2 Antikörper
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects CD182 / IL8RB (middle). No cross reactivity with other proteins.
Kreuzreaktivität (Details)
Species reactivity (tested):Human
Aufreinigung
Immunogen affinity purified
Immunogen
Synthetic peptide mapping at the middle region of human CXCR2 .Remarks: Sequence is identical to the related rat and mouse sequence.
Isotyp
IgG
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Discover our top product CXCR2 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Konservierungsmittel
Sodium azide, Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu CXCR2
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Target
CXCR2
(Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
Andere Bezeichnung
CD182 / IL8RB (CXCR2 Produkte )
Synonyme
CD182 antikoerper, CDw128b antikoerper, CMKAR2 antikoerper, IL8R2 antikoerper, IL8RA antikoerper, IL8RB antikoerper, CXC-R2 antikoerper, CXCR-2 antikoerper, CD128 antikoerper, CDw128 antikoerper, Cmkar2 antikoerper, Gpcr16 antikoerper, IL-8Rh antikoerper, IL-8rb antikoerper, Il8rb antikoerper, mIL-8RH antikoerper, C-X-C motif chemokine receptor 2 antikoerper, chemokine (C-X-C motif) receptor 2 antikoerper, Cxcr2 antikoerper, CXCR2 antikoerper
Hintergrund
CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.Synonyms: CDw128b, CXCR-2, CXCR2, GRO/MGSA receptor, IL-8 receptor type 2, IL8 receptor beta
Gen-ID
3579
NCBI Accession
NP_001548
UniProt
P25025
Pathways
cAMP Metabolic Process
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