CACNA1C Antikörper (C-Term)

Produktnummer ABIN1105620

Produktdetails anti-CACNA1C Antikörper

Target: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Reacts with Human 248 kDa CACNA1C protein. May cross react with Rat, Mouse and other species.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from C-terminal domain of CAC1C protein.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CACNA1C

Target: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Andere Bezeichnung: CACNA1C (CACNA1C Produkte)

Synonyme: CACH2 antikoerper, CACN2 antikoerper, CACNL1A1 antikoerper, CCHL1A1 antikoerper, CaV1.2 antikoerper, LQT8 antikoerper, TS antikoerper, Cav1.2 antikoerper, Cchl1a1 antikoerper, MBC antikoerper, MELC-CC antikoerper, RATIVS302 antikoerper, isl antikoerper, C-LTCC antikoerper, CHCACHA1C antikoerper, ICA antikoerper, cav1.2 antikoerper, ca(v)1.2 antikoerper, CAV1.2 antikoerper, BCR antikoerper, rbc antikoerper, calcium voltage-gated channel subunit alpha1 C antikoerper, calcium channel, voltage-dependent, L type, alpha 1C subunit antikoerper, voltage-dependent L-type calcium channel subunit alpha-1C antikoerper, calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog antikoerper, Red blood cell count antikoerper, RNA, 7SL, cytoplasmic 263, pseudogene antikoerper, CACNA1C antikoerper, Cacna1c antikoerper, cacna1c antikoerper, LOC100442085 antikoerper, cacna1c.S antikoerper, RBC antikoerper, RN7SL263P antikoerper

Hintergrund: CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.Synonyms: CACH2, CACN2, CACNL1A1, CCHL1A1, Calcium channel L type alpha-1 polypeptide isoform 1 cardiac muscle, Cav1.2, Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-gated calcium channel subunit alpha

Gen-ID: 775

NCBI Accession: NP_000710

Pathways: Hormone Transport, Carbohydrate Homeostasis