Aquaporin 4 Antikörper (C-Term)
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- Target Alle Aquaporin 4 (AQP4) Antikörper anzeigen
- Aquaporin 4 (AQP4)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Aquaporin 4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects Aquaporin-4 (C-term). No cross reactivity with other proteins.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
- Aufreinigung
- Immunogen affinity purified
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminal of human AQP4 .Remarks: Sequence is identical to the related rat and mouse sequence.
- Isotyp
- IgG
- Top Product
- Discover our top product AQP4 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Konservierungsmittel
- Sodium azide, Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- Aquaporin 4 (AQP4)
- Andere Bezeichnung
- Aquaporin-4 (AQP4 Produkte)
- Synonyme
- zgc:100922 antikoerper, si:ch211-192k9.1 antikoerper, AQP4 antikoerper, LOC100232616 antikoerper, HMIWC2 antikoerper, MIWC antikoerper, WCH4 antikoerper, AQP-4 antikoerper, AQP4.M23 antikoerper, MIWC2 antikoerper, Miwc antikoerper, aquaporin-4 antikoerper, aquaporin 4 antikoerper, aquaporin 4 L homeolog antikoerper, aqp4 antikoerper, AQP4 antikoerper, aqp4.L antikoerper, Aqp4 antikoerper
- Hintergrund
- Aquaporin 4 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells. The gene of AQP4 is mapped to 18q11.2-q12.1. Similar to other aquaporins, the AQP4 gene is composed of 4 exons encoding 127, 55, 27, and 92 amino acids separated by introns of 0.8, 0.3, and 5.2 kb. Unlike other aquaporins, an alternative coding initiation sequence (designated exon 0) was located 2.7 kb upstream of exon 1. When spliced together, M1 and the subsequent 10 amino acids are encoded by exon 0, the next 11 amino acids and M23 are encoded by exon 1. AQP4 is expressed in astrocytes and is upregulated by direct insult to the central nervous system. AQP4 is the predominant water channel in the brain and has an important role in brain water homeostasis. It is abundant in mammalian brain and is concentrated in astrocytic foot processes at the blood-brain barrier.Synonyms: AQP-4, AQP4, MIWC, Mercurial-insensitive water channel, WCH4
- Gen-ID
- 361
- NCBI Accession
- NP_001641
- UniProt
- P55087
- Pathways
- Sensory Perception of Sound
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