Acetyl-CoA Carboxylase beta Antikörper (Internal Region)

Produktnummer ABIN1105210

Produktdetails anti-Acetyl-CoA Carboxylase beta Antikörper

Target: Acetyl-CoA Carboxylase beta (ACACB)

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase beta Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Sequenz: C-QLGEPDLSDK DRKD

Spezifität: This antibody recognizes ACACB

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography

Immunogen: Synthetic Peptide (C-QLGEPDLSDKDRKD) from the internal region of Human ACACB (NP_001084.2). Genename: ACACB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Acetyl-CoA Carboxylase beta

Target: Acetyl-CoA Carboxylase beta (ACACB)

Andere Bezeichnung: Acetyl-CoA Carboxylase 2 (ACACB Produkte)

Synonyme: F15C21.2 antikoerper, F15C21_2 antikoerper, acetyl-CoA carboxylase 2 antikoerper, ACC2 antikoerper, ACCB antikoerper, HACC275 antikoerper, Acc2 antikoerper, AI597064 antikoerper, AW743042 antikoerper, Accb antikoerper, acetyl-CoA carboxylase 2 antikoerper, acetyl-CoA carboxylase beta antikoerper, acetyl-Coenzyme A carboxylase beta antikoerper, ACC2 antikoerper, ACACB antikoerper, Acacb antikoerper

Hintergrund: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. ACC alpha (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC beta (ACC2) is thought to control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. ACC beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. The gene encoding ACC beta maps to human chromosome 12 and encodes a mitochondiral protein expressed in heart and skeletal muscle. The catalytic core of ACC beta is homologous to that of ACC alpha, except for an additional peptide of about 150 amino acids at the N-terminusSynonyms: ACACB, ACC2, ACCB

Gen-ID: 32

NCBI Accession: NP_001084

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process