TSH receptor Antikörper (Extracellular Domain)

Produktnummer ABIN1104855

Produktdetails anti-TSH receptor Antikörper

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Bindungsspezifität: AA 101-115, Extracellular Domain

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TSH receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Human TSH Receptor. This antibody is expected to recognize reported isoform 1 (NP_000360.2) and isoform 2 (NP_001018046.1). The immunizing peptide sequence corresponds to a part of the extracellular domain.

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%) Monkey, Marmoset, Sheep, Bovine (93%) Galago, Mouse, Rat, Elephant, Panda, Bat, Dog, Feline, Horse, Rabbit, Porcine, Opossum, Guinea pig, Turkey, Zebra finch, Chicken (87%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-SKVTHIEIRNTRNLT from an internal region of human TSH Receptor (NP_000360.2, NP_001018046.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%), Monkey, Marmoset, Sheep, Bovine (93%), Galago, Mouse, Rat, Elephant, Panda, Bat, Dog, Feline, Horse, Rabbit, Porcine, Opossum, Guinea pig, Turkey, Zebra finch, Chicken (87%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: Peptide-ELISA (1:16000), WB (0.5 - 2 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 28kD band observed in Human Thyroid Gland lysates (calculated MW of 28.4kD according to NP_001018046.1). Recommended concentration: 0.5-2 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Andere Bezeichnung: TSH Receptor / TSHR (TSHR Produkte)

Synonyme: CHNG1 antikoerper, LGR3 antikoerper, hTSHR-I antikoerper, AI481368 antikoerper, hypothroid antikoerper, hyt antikoerper, pet antikoerper, TSHRA antikoerper, TSH-R antikoerper, thyroid stimulating hormone receptor antikoerper, tshr antikoerper, TSHR antikoerper, Tshr antikoerper

Hintergrund: Name/Gene ID: TSHR
Subfamily: Glycoprotein hormone
Family: GPCR

Synonyms: TSHR, CHNG1, HTSHR-I, LGR3, Thyrotrophin receptor, TSH-R, TSH receptor, Thyrotropin receptor

Gen-ID: 7253

NCBI Accession: NP_000360, NP_001018046

UniProt: P16473

Pathways: Thyroid Hormone Synthesis