LCK Antikörper (AA 39-52)

Produktnummer ABIN1102819

Produktdetails anti-LCK Antikörper

Target: LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Bindungsspezifität: AA 39-52

Reaktivität: Human, Maus, Rind (Kuh), Schaf, Pferd, Kaninchen, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser LCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Human LCK. This antibody is not expected to cross-react with other tyrosine protein kinases. Reported variants represent identical protein: NP_005347.3, NP_001036236.1

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Mouse, Sheep, Bovine, Horse, Rabbit, Porcine (100%) Galago, Rat, Elephant, Panda, Guinea pig, Turkey (93%) Dog, Opossum, Chicken (86%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-RNGSEVRDPLVTYE from an internal region (near N-terminus) of human LCK (NP_005347.3). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Mouse, Sheep, Bovine, Horse, Rabbit, Porcine (100%), Galago, Rat, Elephant, Panda, Guinea pig, Turkey (93%), Dog, Opossum, Chicken (86%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: Peptide-ELISA (1:16000), WB (0.1 - 0.3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 60kD band observed in Human Thymus lysates (calculated MW of 58.0kD according to NP_005347.3). Recommended concentration: 0.1-0.3 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu LCK

Target: LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

Andere Bezeichnung: p56lck / LCK (LCK Produkte)

Synonyme: zgc:136695 antikoerper, LCK antikoerper, Hck-3 antikoerper, Lsk antikoerper, Lskt antikoerper, p56 antikoerper, p56Lck antikoerper, LSK antikoerper, YT16 antikoerper, p56lck antikoerper, pp58lck antikoerper, P56LCK antikoerper, tkl antikoerper, Lck1 antikoerper, Lcktkr antikoerper, LCK proto-oncogene, Src family tyrosine kinase antikoerper, lymphocyte protein tyrosine kinase antikoerper, lck antikoerper, LCK antikoerper, Lck antikoerper

Hintergrund: Name/Gene ID: LCK
Subfamily: Src
Family: Protein Kinase

Synonyms: LCK, Lck kinase, LSK, p56-LCK, Pp58lck, Tyrosine-protein kinase Lck, p56lck, Protein YT16, Proto-oncogene Lck, YT16

Gen-ID: 3932

NCBI Accession: NP_005347

UniProt: P06239

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling