RRAS2 Antikörper (C-Term)

Produktnummer ABIN1077448

Produktdetails anti-RRAS2 Antikörper

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Two isoforms of RRAS2 exists as a result of alternative splicing event.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal RRAS2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human RRAS2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RRAS2 antibody can be used for detection of RRAS2 by Western blot at 1 - 2 μg/mL.

Kommentare:

(CT) Related RAS viral (r-ras) oncogene homolog 2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Details zu RRAS2

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Andere Bezeichnung: RRAS2 (RRAS2 Produkte)

Synonyme: TC21 antikoerper, 2610016H24Rik antikoerper, C86394 antikoerper, Ras-related protein R-Ras2 antikoerper, RAS related 2 antikoerper, related RAS viral (r-ras) oncogene 2 antikoerper, related RAS viral (r-ras) oncogene homolog 2 antikoerper, TVAG_453070 antikoerper, Bm1_46660 antikoerper, RRAS2 antikoerper, Rras2 antikoerper

Hintergrund: Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%. RRAS2 is a small GTPbinding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.
Synonyms: Related RAS viral (r-ras) oncogene homolog 2, Ras-like protein TC21, Ras-related protein R-Ras2, TC21, Teratocarcinoma oncogene

Molekulargewicht: 22 kDa

Gen-ID: 22800

NCBI Accession: NP_036382