CARM1 Antikörper (N-Term)

Produktnummer ABIN1077435

Produktdetails anti-CARM1 Antikörper

Target: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal CARM1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CARM1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CARM1 antibody can be used for detection of CARM1 by Western blot at 1 - 2 μg/mL.

Kommentare:

(NT) Coactivator-associated arginine methyltransferase 1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: CARM1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu CARM1

Target: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Andere Bezeichnung: CARM1 (CARM1 Produkte)

Synonyme: NV18905 antikoerper, prmt4 antikoerper, PRMT4 antikoerper, Prmt4 antikoerper, si:dkey-204f11.63 antikoerper, zgc:100805 antikoerper, coactivator associated arginine methyltransferase 1 antikoerper, coactivator associated arginine methyltransferase 1 L homeolog antikoerper, coactivator-associated arginine methyltransferase 1 antikoerper, histone-arginine methyltransferase CARM1 antikoerper, CARM1 antikoerper, carm1.L antikoerper, Carm1 antikoerper, carm1 antikoerper, LOC100352221 antikoerper

Hintergrund: Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. CARM1 functions as a transcriptional co-activator for various nuclear receptors and NF-kB. It has also been shown to methylate histone H3 arginines, inhibiting the binding of corepressors and protecting chromatin from deacetylation, thereby facilitating transcription.
Synonyms: Coactivator-associated arginine methyltransferase 1, PRMT4

Molekulargewicht: 67 kDa (calculated)

Gen-ID: 10498

NCBI Accession: NP_954592

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation