BATF Antikörper (N-Term)

Produktnummer ABIN1077388

Produktdetails anti-BATF Antikörper

Target: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BATF Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Spezifität: Multiple isoforms of BATF are known to exist. Despite its predicted molecular weight, BATF often migrates at a higher than expected molecular weight.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: BATF antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BATF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: BATF antibody can be used for detection of BATF by Western blot at 0.5 μg/mL. For immunofluorescence start at 20 μg/mL.

Kommentare:

(NT) B-cell activating transcription factor

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: BATF antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu BATF

Target: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Andere Bezeichnung: BATF (BATF Produkte)

Synonyme: B-ATF antikoerper, si:ch211-153j24.4 antikoerper, BATF1 antikoerper, SFA-2 antikoerper, SFA2 antikoerper, basic leucine zipper transcription factor, ATF-like antikoerper, basic leucine zipper ATF-like transcription factor antikoerper, batf antikoerper, BATF antikoerper, Batf antikoerper

Hintergrund: BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
Synonyms: B-cell activating transcription factor, BATF1, basic leucine zipper transcriptional factor ATF-like, SF-HT-activated gene 2 protein, SFA-2, SFA2

Molekulargewicht: 14 kDa

Gen-ID: 10538

NCBI Accession: NP_006390