TNNI3 Antikörper

Produktnummer ABIN1045363

Produktdetails anti-TNNI3 Antikörper

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNNI3 Antikörper ist unkonjugiert

Applikation: ELISA

Spezifität: Reacts equally with free cardiac troponin I and cardiac troponin I forming complexes with other troponin components. Not affected by heparin, phosphorylation and oxidation.

Kreuzreaktivität: Human

Kreuzreaktivität (Details): No cross-reactivity with skeletal muscle troponin I.

Aufreinigung: Protein G purified

Reinheit: > 95 %

Immunogen: Recombinant Human Cardiac Troponin I protein

Klon: 11D2E10

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Other species are not tested. Please decide the specificity by homology

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Referenzen für anti-TNNI3 Antikörper (ABIN1045363)

Stein, Janjua, Matta, Pathak, Jaweesh, Alrifai, Chughtai: "Prognosis based on creatine kinase isoenzyme MB, cardiac troponin I, and right ventricular size in stable patients with acute pulmonary embolism." in: The American journal of cardiology, Vol. 107, Issue 5, pp. 774-7, (2011) (PubMed).

Goel, Beith: "Troponin I as a predictor for trastuzumab-related cardiotoxicity: current data do not provide mechanistic insights or allow for incorporation into clinical practice." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 29, Issue 7, pp. e175-6, (2011) (PubMed).

Xue, Clopton, Peacock, Maisel: "Serial changes in high-sensitive troponin I predict outcome in patients with decompensated heart failure." in: European journal of heart failure, Vol. 13, Issue 1, pp. 37-42, (2010) (PubMed).

Paparella, Scrascia, Paramythiotis, Guida, Magari, Malvindi, Favale, de Luca Tupputi Schinosa: "Preoperative cardiac troponin I to assess midterm risks of coronary bypass grafting operations in patients with recent myocardial infarction." in: The Annals of thoracic surgery, Vol. 89, Issue 3, pp. 696-702, (2010) (PubMed).

John, Woodward, Wang, Yan, Fisher, Kinasewitz, Heiselman: "Troponin-I as a prognosticator of mortality in severe sepsis patients." in: Journal of critical care, Vol. 25, Issue 2, pp. 270-5, (2010) (PubMed).

van Geene, van Swieten, Noyez: "Cardiac troponin I levels after cardiac surgery as predictor for in-hospital mortality." in: Interactive cardiovascular and thoracic surgery, Vol. 10, Issue 3, pp. 413-6, (2010) (PubMed).

Napan, Kashinath, Kadri, Orig, Khadra: "Prognostic significance of preprocedural troponin-I in patients with non-ST elevation acute coronary syndromes undergoing percutaneous coronary intervention." in: Coronary artery disease, Vol. 21, Issue 5, pp. 261-5, (2010) (PubMed).

Bonaca, Scirica, Sabatine, Dalby, Spinar, Murphy, Jarolim, Braunwald, Morrow: "Prospective evaluation of the prognostic implications of improved assay performance with a sensitive assay for cardiac troponin I." in: Journal of the American College of Cardiology, Vol. 55, Issue 19, pp. 2118-24, (2010) (PubMed).

Tsutamoto, Kawahara, Nishiyama, Yamaji, Fujii, Yamamoto, Horie: "Prognostic role of highly sensitive cardiac troponin I in patients with systolic heart failure." in: American heart journal, Vol. 159, Issue 1, pp. 63-7, (2010) (PubMed).

Oshima, Kunimoto, Takahashi, Mohara, Takeyoshi, Hinohara, Okawa, Saito: "Postoperative cardiac troponin I (cTnI) level and its prognostic value for patients undergoing mitral valve surgery." in: International heart journal, Vol. 51, Issue 3, pp. 166-9, (2010) (PubMed).

Zahid, Good, Singla, Sonel: "Clinical significance of borderline elevated troponin I levels across different assays in patients with suspected acute coronary syndrome." in: The American journal of cardiology, Vol. 104, Issue 2, pp. 164-8, (2009) (PubMed).

Fruchter, Yigla: "Cardiac troponin-I predicts long-term mortality in chronic obstructive pulmonary disease." in: COPD, Vol. 6, Issue 3, pp. 155-61, (2009) (PubMed).

Alonso Martínez, Annicchérico Sánchez, Urbieta Echezarreta, García Sanchotena, Ezcurra Ibáñez, Lasa Inchausti: "[Clinical usefulness of troponin I in acute pulmonary embolism]." in: Medicina clínica, Vol. 133, Issue 6, pp. 201-5, (2009) (PubMed).

Apple: "Tissue specificity of cardiac troponin I, cardiac troponin T and creatine kinase-MB." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 284, Issue 2, pp. 151-9, (1999) (PubMed).

Details zu TNNI3

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Andere Bezeichnung: TNNI3 (TNNI3 Produkte)

Synonyme: CMD1FF antikoerper, CMD2A antikoerper, CMH7 antikoerper, RCM1 antikoerper, TNNC1 antikoerper, cTnI antikoerper, CMD1Z antikoerper, CMH13 antikoerper, TN-C antikoerper, TNC antikoerper, TNNC antikoerper, Tn1 antikoerper, TnIc antikoerper, ctnIc antikoerper, XTnIc antikoerper, c-troponin antikoerper, cTNT antikoerper, cmh7 antikoerper, ctni antikoerper, tnnc1 antikoerper, TNNI3 antikoerper, TnI antikoerper, cTNI antikoerper, AI874626 antikoerper, TnC antikoerper, cTnC antikoerper, tncc antikoerper, Tncc antikoerper, troponin I3, cardiac type antikoerper, troponin C1, slow skeletal and cardiac type antikoerper, troponin I, cardiac 3 antikoerper, troponin I type 3 (cardiac) antikoerper, troponin I3, cardiac type S homeolog antikoerper, troponin I3, cardiac type L homeolog antikoerper, cardiac troponin I antikoerper, troponin C, cardiac/slow skeletal antikoerper, TNNI3 antikoerper, TNNC1 antikoerper, Tnni3 antikoerper, tnni3.S antikoerper, tnni3.L antikoerper, tnni3 antikoerper, LOC100462680 antikoerper, Tnnc1 antikoerper

Hintergrund:

Background: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.

Aliases: CTnI

UniProt: P19429