Interleukin 32 alpha (IL32A) Antikörper (Biotin)

Details zu Produkt Nr. ABIN1043804, Anbieter: Anmelden zum Anzeigen
Antigen
  • IL-32alpha
  • IL-32beta
  • IL-32delta
  • IL-32gamma
  • NK4
  • TAIF
  • TAIFa
  • TAIFb
  • TAIFc
  • TAIFd
  • interleukin 32
  • IL32
Reaktivität
Human
16
Wirt
Kaninchen
7
7
2
Klonalität
Polyklonal
Konjugat
Biotin
2
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
8
7
6
3
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-32A protein.
Immunogen Type: RecombinantProtein
Isotyp IgG
Spezifität This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-32A in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
Produktmerkmale IL-32A (also known as Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32alpha, Interleukin-32 and IL-32 isoform 4) is a member of the cytokine family. IL-32a is a secreted protein selectively expressed in lymphocytes and plays a role in innate and adaptive immune responses. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha and IL-8. It induces typical cytokine pathways of NF-kB and p38 MAPK. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Reinigung purified
Andere Bezeichnung IL-32A (IL32A Antibody Abstract)
Hintergrund IL-32A (also known as Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32α, Interleukin-32 and IL-32 isoform 4) is a member of the cytokine family. IL-32a is a secreted protein selectively expressed in lymphocytes and plays a role in innate and adaptive immune responses. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFα and IL-8. It induces typical cytokine pathways of NF-kB and p38 MAPK. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms: IL-32A, Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32α, Interleukin-32 and IL-32 isoform 4.
Gen-ID 9235, 61658634
UniProt P24001
Applikationshinweise This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 15 kDa in size corresponding to native human IL-32α protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
Kommentare

Gene Name: IL32

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
Konzentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Haltbarkeit 12 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Interleukin 32 alpha (IL32A) antibody (Biotin) (ABIN1043804) Western blot using HRP conjugated anti-Human IL-32A antibody shows detection of a ban...
Produkt verwendet in: Nishida, Andoh, Inatomi, Fujiyama: "Interleukin-32 expression in the pancreas." in: The Journal of biological chemistry, Vol. 284, Issue 26, pp. 17868-76, 2009 (PubMed).

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