Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
analysis of the mechanism underlying synergistic up-regulation of PDE4B2 via a cross-talk between PKA-Cbeta and p65 (zeige GORASP1 Proteine)
The gene polymorphism loci rs12132032 in PRKACB maybe a potential risk factor for anencephaly in Chinese population from Shanxi, while gender susceptibility may influence the correlation.
The previously unknown small molecule inhibitor-dependent interaction of Cbeta1 with the cell cycle and apoptosis regulatory protein-1 was verified.
PGE (zeige LIPF Proteine)(2)-induced CYP1B1 (zeige CYP1B1 Proteine) expression is mediated by ligand-independent activation of the ERalpha (zeige ESR1 Proteine) pathway as a result of the activation of ERK (zeige EPHB2 Proteine), Akt (zeige AKT1 Proteine), and PKA in breast cancer cells.
Data show that PI3K activation and PIP3 production lead to recruitment of the PKB/beta-arrestin/PDE4 complex to the membrane via the PKB PH domain, resulting in degradation of the TCR-induced cAMP pool and allowing full T-cell activation to proceed.
Results suggest that PKA can negatively regulate ERalpha (zeige ESR1 Proteine), at least in part, through FoxH1 (zeige FOXH1 Proteine).
c-MYC (zeige MYC Proteine) induces the activity of protein kinase A by inducing the transcription of the gene encoding the PKA catalytic subunit beta in multiple tissues, independent of cell proliferation by direct binding of c-MYC (zeige MYC Proteine) to promoter sequences.
Data describe the identification of a variant of the beta catalytic subunit of cyclic AMP (zeige APRT Proteine)-dependent protein kinase (zeige CDK7 Proteine) (PKACbeta) as a p75 neurotrophin receptor (zeige NGFR Proteine)(NTR)-interacting protein, which phosphorylates p75(NTR (zeige NGFR Proteine)) at Ser304.
there are abnormalities in [3H]cAMP binding and catalytic activity kinase A in brain of depressed suicide victims, which could be due to reduced expression of RIIbeta (zeige PRKAR2B Proteine) and Cbeta.
there is a PKA-Cbeta-mediated inhibitory mechanism of p73 (zeige TP73 Proteine) function
critically involved in mediating the phosphorylation of AMP (zeige TMPRSS5 Proteine) kinase promoted by hydrogen peroxide in endothelial cells.
Protein kinase A signaling explains vasopressin (zeige AVP Proteine)-mediated regulation of membrane trafficking and gene transcription.
We suggest a role of the PRKACB gene splice variant Cbeta2 in regulating innate as well as adaptive immune sensitivity in vivo.
Gli2 and Gli3 (zeige GLI3 Proteine) are dephosphorylated and activated in cilia and that impaired Gli2 and Gli3 (zeige GLI3 Proteine) processing in Ta3 (zeige HSP90B1 Proteine) mutant is at least in part due to a decrease in Gli2 and Gli3 (zeige GLI3 Proteine) phosphorylation.
Data indicate that TRPV4 activity and TRPV4 trafficking are under discrete but synergistic control of PKC- and PKA-dependent pathways.
Studies identified three novel alternatively spliced transcript variants of the mouse protein kinase A catalytic beta subunit (zeige POLG Proteine) (Cbeta) gene designated Cbeta5, Cbeta6 and Cbeta7.
These data suggest that both developmental and tumor phenotypes caused by Prkar1a (zeige PRKAR1A Proteine) mutation result from excess PKA activity due to PKA-Ca.
crystal structure of the catalytic subunit in complex with ADP, aluminum fluoride, Mg2 (zeige MCOLN1 Proteine)+ ions and a substrate peptide was determined at 2.0 A resolution
glucose and glucagon (zeige GCG Proteine)-like polypeptide-1 caused translocation of Calpha (zeige PRKACA Proteine) to the nucleus and of Cbeta to the plasma membrane and the nucleus, but did not affect the distribution of Cgamma in pancreatic beta-cells
Protein kinase A, C beta subunit (zeige POLG Proteine) is not essential for neuronal development or function but may play a more subtle role in memory that is modulated by strain-specific genetic modifiers.
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Several alternatively spliced transcript variants encoding distinct isoforms have been observed.
, cAMP-dependent protein kinase catalytic beta subunit isoform 4ab
, cAMP-dependent protein kinase catalytic subunit beta
, protein kinase A catalytic subunit beta
, p70 S6 kinase
, protein kinase, cAMP-dependent, catalytic, beta a
, C-beta subunit
, protein kinase, cAMP-dependent, catalytic, beta
, cAMP-dependent protein kinase C beta