HsTx1

Produktnummer ABIN1540075

Produktdetails

Target: HsTx1 (HSTX1) (Hybrid Sterility, X Chromosome 1 (HSTX1))

Applikation: Blocking Reagent (BR)

Verwendungszweck: HsTx1 is a Kv1.3 channel blocker

Sequenz: Ala-Ser-Cys3-Arg-Thr-Pro-Lys-Asp-Cys9-Ala-Asp-Pro-Cys13-Arg-Lys-Glu-Thr-Gly-Cys19-Pro-Tyr-Gly-Lys-Cys24-Met-Asn-Arg-Lys-Cys29-Lys-Cys31-Asn-Arg-Cys34-NH2Disulfide bonds between Cys3-Cys24, Cys9-Cys29,Cys13-Cys31 and Cys19-Cys34

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Antigendetails

Target: HsTx1 (HSTX1) (Hybrid Sterility, X Chromosome 1 (HSTX1))

Andere Bezeichnung: HsTx1

Hintergrund: HsTx1 is a member of the a-KTx6 family of toxins active on voltage-gated K+ v1.3 channels (Kd close to 10 pM). It is also very active on Kv1.2 channels (Kd around 7 nM). It is however inactive on apamin-sensitive SK channels. It is one of the most potent toxins active on K channels.

Molekulargewicht: 3819.87 Da