alpha-conotoxin MI (alpha conotoxin MI)
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- Target
- alpha-conotoxin MI
- Applikation
- Blocking Reagent (BR)
- Verwendungszweck
- alpha-conotoxin MI blocks nAChR
- Sequenz
- Gly-Arg-Cys3-Cys4-His-Pro-Ala-Cys8-Gly-Lys-Asn-Tyr-Ser-Cys14-NH2Disulfide bonds between Cys3-Cys8 and Cys4-Cys14
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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-
- Target
- alpha-conotoxin MI
- Hintergrund
- Alpha-conotoxin MI has been isolated from the venom of the cone snail Conus magus. This conotoxin acts on postsynaptic membranes. It binds onto and blocks nicotinic acetylcholine receptors (nAChR). alpha-conotoxin MI blocks mammalian nAChR composed of alpha1/delta subunits with high potency and alpha1/gamma with low potency.
- Molekulargewicht
- 1495.08 Da
- CAS-Nummer
- 83481-45-2
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