thromboxane A Synthase 1 (Platelet) (TBXAS1) ELISA Kits

TBXAS1 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen thromboxane A Synthase 1 (Platelet) Antikörper (89) und thromboxane A Synthase 1 (Platelet) Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
TBXAS1 6916 P24557
TBXAS1 21391 P36423
TBXAS1 24886 P49430
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Top thromboxane A Synthase 1 (Platelet) ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.067 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$713.90
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Ratte 0.094 ng/mL 0.15 ng/mL - 10 ng/mL A typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$707.69
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Schwein
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Meerschweinchen
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Kaninchen
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Maus
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$707.14
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Rind (Kuh)
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$1,029.60
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Weitere ELISA Kits für thromboxane A Synthase 1 (Platelet) Interaktionspartner

Human thromboxane A Synthase 1 (Platelet) (TBXAS1) Interaktionspartner

  1. RS41708TT is not only independent risk factor for symptomatic carotid artery or intracranial arterial stenosis, but is also independent risk predictor for neurologic deterioration in ischemic stroke patients.

  2. Sequencing revealed two novel biallelic variants of unknown significance within the thromboxane A synthase gene, TBXAS1 (c.266T > C; c.989T > C), bioinformatically predicted to disrupt the protein. TBXAS1 mutations result in Ghosal hematodiaphyseal dysplasia (OMIM 231095), the autosomal recessive syndrome associated with abnormal bone structure and BMF.

  3. TXAS1 rs2267679TT and rs41708TT genotypes are associated with carotid plaque vulnerability, platelet activation and TXA2 levels in ischemic stroke patients.

  4. the administration of salted drinking water (2.7% NaCl) to wild-type mice resulted in elevated placental TXA2 synthase (TXAS) and plasma thromboxane A2, but not prostacyclin, levels, which was also found in clinical preeclampsia placenta samples.

  5. Single nucleotide polymorphisms of TBXAS1 are associated with susceptibility to gout in ethnic Han males population.

  6. The cardiovascular events significantly morefrequently occurred during 12 and 18 months in resistant diabetics and in the patients with an allele lacking the *2/*3 CYP2C9 gene function and AT/TT polymorphism of the thromboxane synthase gene TBS1.

  7. The carriage of Thromboxane A synthase 1 gene polymorphism AA was shown to affect the risk of clopidogrel resistance.

  8. study suggests that the anti-tumor effect of glycyrrhizin in lung adenocarcinoma is, at least in part, TxAS-dependent.

  9. 12-HHT is produced by both TxAS-dependent and TxAS-independent pathways in vitro and in vi

  10. In this study we have showed, for the first time, a significant role of the minor allele rs6962291 of TBXAS1 in patients with NSAID acute cutaneous hypersensitivity.

  11. The increased Km and decreased Vmax values observed with L357V suggest that this variant may generate less TXA2 at the low levels of PGH2 expected in vivo, raising the possibility of attenuated signaling through the thromboxane pathway.

  12. Data show that that DNA methylation of the TBXAS1 promoter was decreased and thromboxane synthase expression was increased in omental arteries of preeclamptic women as compared with normal pregnant women.

  13. these results showed that visfatin promoted IL-8 production by upregulation of TXAS, leading to angiogenic activation in endothelial cells.

  14. Rs10487667 polymorphism in the CYP5A1 gene might be a risk factor of myocardial infarction in the Uigur population in Xinjiang.

  15. Data suggest that targeting thromboxane synthase alone, or in combination with conventional chemotherapy is a potential therapeutic strategy for NSCLC.

  16. The rare allele of rs6962291 may play a protective role against aspirin hypersensitivity via a lower catalytic activity of the TBXAS1 gene, attributed to the increase of a nonfunctioning isoform of TBXAS1.

  17. The TC genotype and T allele of thromboxane synthase are risk factors of myocardial infarction.

  18. Apoptosis induced in lung cancer cells by the thromboxane synthase inhibitor 1-benzylimidazole is associated with the over-production of ROS and the reduction of NF-kappaB.

  19. In humans, TXAS was expressed in the atherosclerotic lesion, associated with increased inflammatory cells, in particular M2 polarized macrophages, and increased in atherosclerotic lesions of patients with recent symptoms of thrombotic events.

  20. Gene transfer of thromboxane A(2) synthase and prostaglandin I(2) synthase antithetically altered tumor angiogenesis and tumor growth.

Mouse (Murine) thromboxane A Synthase 1 (Platelet) (TBXAS1) Interaktionspartner

  1. this study shows that genetic depletion of Thromboxane A2/Thromboxane-Prostanoid Receptor signaling prevents microvascular dysfunction in ischemia reperfusion injury

  2. the administration of salted drinking water (2.7% NaCl) to wild-type mice resulted in elevated placental TXA2 synthase (TXAS) and plasma thromboxane A2, but not prostacyclin, levels, which was also found in clinical preeclampsia placenta samples.

  3. 12-HHT is produced by both TxAS-dependent and TxAS-independent pathways in vitro and in vi

  4. TXAS mRNA expression was increased within the vascular wall in mouse models of atherosclerosis with advanced lesions.

  5. thromboxane synthase, prostacyclin synthase and thromboxane receptor have roles in atherosclerotic lesions and correlate with plaque composition

  6. minimal level of protein kinase A activity is required for the steroidogenic effect of the TBXAS inhibitor and that inhibition of TBXAS activity or its expression increase the steroidogenic sensitivity of MA-10 mouse Leydig cells to cAMP stimulation

thromboxane A Synthase 1 (Platelet) (TBXAS1) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit TBXAS1

  • thromboxane-A synthase (PTRG_00454) Antikörper
  • thromboxane-A synthase (PTRG_06796) Antikörper
  • Thromboxane-A synthase (thas) Antikörper
  • thromboxane A synthase 1 (TBXAS1) Antikörper
  • thromboxane A synthase 1 (platelet) (tbxas1) Antikörper
  • thromboxane A synthase 1, platelet (Tbxas1) Antikörper
  • thromboxane A synthase 1 (Tbxas1) Antikörper
  • BDPLT14 Antikörper
  • CYP5 Antikörper
  • CYP5A1 Antikörper
  • GHOSAL Antikörper
  • TBXAS1 Antikörper
  • THAS Antikörper
  • TS Antikörper
  • TXAS Antikörper
  • TXS Antikörper
  • wu:fk19d08 Antikörper
  • zgc:136708 Antikörper

Bezeichner auf Proteinebene für TBXAS1

thromboxane-A synthase , Thromboxane-A synthase , thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) , thromboxane A synthase 1 (platelet) , thromboxane-A synthase-like , TXA synthase , cytochrome P450 5A1 , cytochrome P450, family 5, subfamily A, polypeptide 1 , platelet, cytochrome P450, subfamily V , TXS , thromboxane A synthase 1, platelet , ThromboxA ane synthase 1

GENE ID SPEZIES
6338652 Pyrenophora tritici-repentis Pt-1C-BFP
6345060 Pyrenophora tritici-repentis Pt-1C-BFP
100306773 Salmo salar
418101 Gallus gallus
463774 Pan troglodytes
482771 Canis lupus familiaris
711748 Macaca mulatta
792041 Danio rerio
100173366 Pongo abelii
100481563 Ailuropoda melanoleuca
100580072 Nomascus leucogenys
6916 Homo sapiens
397112 Sus scrofa
509326 Bos taurus
21391 Mus musculus
24886 Rattus norvegicus
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