Zinc Finger, DHHC-Type Containing 13 Proteine (ZDHHC13)

Palmitoyltransferase for HD and GAD2 (By similarity).

alle Proteine anzeigen Gen GeneID UniProt
Maus ZDHHC13 ZDHHC13 243983 Q9CWU2
Human ZDHHC13 ZDHHC13 54503 Q8IUH4
Ratte ZDHHC13 ZDHHC13 365252  
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$6,616.87
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Weitere Proteine zu Zinc Finger, DHHC-Type Containing 13 (ZDHHC13) Interaktionspartnern

Mouse (Murine) Zinc Finger, DHHC-Type Containing 13 (ZDHHC13) Interaktionspartner

  1. Data show that the ankyrin repeat (AR) domains of S-acyltransferases zDHHC17 (zeige ZDHHC17 Proteine) and zDHHC13 recognize peptide sequence in several unrelated proteins.

  2. Zdhhc13 regulates Smad6 during BMP-dependent signaling and early lineage decisions in an in vitro cell model.

  3. Loss of Hip14 (zeige ZDHHC17 Proteine) and Hip14l leads to early embryonic lethality at day embryonic day 10-11 due to failed chorioallantoic fusion.

  4. Zdhhc13 is a novel regulator of postnatal skeletal development and bone mass acquisition.

  5. Hip14l-deficient mice develop adult-onset, neuropathological deficits characteristic of Huntington disease (zeige HTT Proteine).

  6. A second gene trap allele of Zdhhc13 has the same phenotypes, suggesting that this is a loss of function allele.

  7. huntingtin (zeige HTT Proteine) interacting protein genes, HIP14 (zeige ZDHHC17 Proteine) and HIP14L, encode Mg2 (zeige MCOLN1 Proteine)+ transport proteins that are regulated by their innate palmitoyl acyltransferases thus fulfilling the characteristics of "chanzymes."

Human Zinc Finger, DHHC-Type Containing 13 (ZDHHC13) Interaktionspartner

  1. This suggests that altered HIP14 (zeige ZDHHC17 Proteine)-HTT (zeige HTT Proteine) and HIP14L-HTT (zeige HTT Proteine) interactions in the presence of the HD mutation reduces palmitoylation and promotes mislocalization of HTT (zeige HTT Proteine) and other HIP14 (zeige ZDHHC17 Proteine)/HIP14L substrates

  2. Data show that deletion of huntingtin (zeige HTT Proteine) protein (HTT (zeige HTT Proteine)) amino acids 1-427 abolishes the interaction of HTT (zeige HTT Proteine) with palmitoyl acyltransferases huntingtin interacting protein 14 (HIP14 (zeige ZDHHC17 Proteine)) and huntingtin interacting protein 14 (zeige ZDHHC17 Proteine)-like (HIP14L).

  3. huntingtin (zeige HTT Proteine) interacting protein genes, HIP14 (zeige ZDHHC17 Proteine) and HIP14L, encode Mg2 (zeige MUC7 Proteine)+ transport proteins that are regulated by their innate palmitoyl acyltransferases thus fulfilling the characteristics of "chanzymes."

ZDHHC13 Protein Überblick

Protein Überblick

Palmitoyltransferase for HD and GAD2 (By similarity). Mediates Mg(2+) transport (By similarity).

Genbezeichner und Symbole assoziert mit ZDHHC13

  • zinc finger DHHC-type containing 13 (ZDHHC13)
  • zinc finger, DHHC domain containing 13 (Zdhhc13)
  • zinc finger, DHHC-type containing 13 (zdhhc13)
  • zinc finger, DHHC-type containing 13 (Zdhhc13)
  • 2410004E01Rik Protein
  • C530010M18 Protein
  • HIP3RP Protein
  • HIP14L Protein
  • kojak Protein
  • skc4 Protein
  • wu:fb06e01 Protein
  • wu:fc39g10 Protein
  • wu:fi22e09 Protein
  • ZDHHC13 Protein
  • zgc:101690 Protein

Bezeichner auf Proteinebene für ZDHHC13

zinc finger, DHHC-type containing 13 , DHHC-13 , HIP14-related protein , huntingtin-interacting protein 14-related protein , palmitoyltransferase ZDHHC13 , probable palmitoyltransferase ZDHHC13 , zinc finger DHHC domain-containing protein 13 , fi22e09 , huntingtin interacting protein HIP3RP , huntingtin-interacting protein HIP3RP , putative MAPK-activating protein PM03 , putative NF-kappa-B-activating protein 209 , zinc finger, DHHC domain containing 13 , Probable palmitoyltransferase ZDHHC13

GENE ID SPEZIES
451071 Pan troglodytes
613004 Canis lupus familiaris
100071954 Equus caballus
243983 Mus musculus
494107 Danio rerio
422980 Gallus gallus
54503 Homo sapiens
514176 Bos taurus
365252 Rattus norvegicus
100174171 Pongo abelii
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