TEN1 Telomerase Capping Complex Subunit Homolog (S. Cerevisiae) Proteine (TEN1)

C17ORF106, or TEN1, appears to function in a telomere-associated complex with STN1 (OBFC1\; MIM 613128) and CTC1 (C17ORF68\; MIM 613129) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009].. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TEN1 100134934 Q86WV5
TEN1 69535 Q9D7K2
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
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Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$492.31
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TEN1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human

Mouse (Murine)

Weitere Proteine zu TEN1 Telomerase Capping Complex Subunit Homolog (S. Cerevisiae) (TEN1) Interaktionspartnern

Human TEN1 Telomerase Capping Complex Subunit Homolog (S. Cerevisiae) (TEN1) Interaktionspartner

  1. CTC1/STN1 (zeige STON1 Proteine)/TEN1 (CST (zeige GAL3ST1 Proteine)) deficiency diminishes HU-induced RAD51 (zeige RAD51 Proteine) foci formation.

  2. The findings imply that theCTC1/STN1/TEN1 complex(CST )complex plays an important role in regulating telomere maintenance in alternative-lengthening of telomeres(ALT) cells.

  3. TERT (zeige TERT Proteine)-mediated G-strand extension and Ctc1-Stn1 (zeige STON1 Proteine)-Ten1-mediated C-strand fill-in are equally important for telomere length maintenance.

  4. reveal a critical role for human Stn1 (zeige STON1 Proteine) in telomere length maintenance and function, supporting the model that efficient replication of telomeric repeats is critical for long-term viability of normal somatic mammalian cells

  5. The mammalian CST (zeige GAL3ST1 Proteine) (CTC1-STN1 (zeige STON1 Proteine)-TEN1) complex is directly involved at several stages of telomere end formation and CST (zeige GAL3ST1 Proteine) seems to play critical roles in coordinating telomerase elongation and fill-in synthesis to complete telomere replication.

  6. data indicate that hTen1 is critical for the telomeric function of hCST (zeige CMPST Proteine), both in telomere protection and downregulation of telomerase function

  7. TEN1 likely functions in conjunction with CTC1 and STN1 (zeige STON1 Proteine) at the telomere and elsewhere in the genome.

  8. the human CST (zeige GAL3ST1 Proteine) (CTC1, STN1 (zeige STON1 Proteine) and TEN1) complex, previously implicated in telomere protection and DNA metabolism, inhibits telomerase activity through primer sequestration and physical interaction with the protection of telomeres 1 (POT1 (zeige POT1 Proteine))-TPP1 (zeige TPP1 Proteine) telomerase processivity factor

  9. Ctc1-Stn1 (zeige STON1 Proteine)-Ten1 is a replication protein A (RPA (zeige RPA1 Proteine))-like complex that is not directly involved in conventional DNA replication at forks but plays a role in DNA metabolism frequently required by telomeres.

TEN1 Telomerase Capping Complex Subunit Homolog (S. Cerevisiae) (TEN1) Protein Überblick

Protein Überblick

C17ORF106, or TEN1, appears to function in a telomere-associated complex with STN1 (OBFC1\; MIM 613128) and CTC1 (C17ORF68\; MIM 613129) (Miyake et al., 2009

Genbezeichner und Symbole assoziert mit TEN1

  • TEN1, CST complex subunit (TEN1)
  • TEN1 telomerase capping complex subunit (Ten1)
  • 2310004N24Rik Protein
  • C17orf106 Protein

Bezeichner auf Proteinebene für TEN1

CST complex subunit TEN1 , TEN1 telomerase capping complex subunit homolog , protein telomeric pathways with STN1 homolog , telomere length regulation protein TEN1 homolog , telomeric pathways in association with Stn1, number 1

GENE ID SPEZIES
100134934 Homo sapiens
69535 Mus musculus
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