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The product of SSX5 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. Zusätzlich bieten wir Ihnen Synovial Sarcoma, X Breakpoint 5 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal SSX5 Primary Antibody für IF, WB - ABIN520522 : Smith, Cronk, Lang, McNeel: Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer. in Cancer research 2011 (PubMed)
Two kinds of cancer-testis antigen, SSX-2 (zeige SSX2 Antikörper) and SSX-5 showed high-specific and high-frequent expression in hepatocellular carcinoma tissues, but neither of them could be detected in adjacent non-HCC (zeige FAM126A Antikörper) tissues.
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X\;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
synovial sarcoma, X breakpoint 5 , protein SSX5