SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Proteine (SPSB2)

SPSB2 encodes encodes a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. Zusätzlich bieten wir Ihnen SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Antikörper (23) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SPSB2 84727 Q99619
SPSB2 14794 O88838
SPSB2 297592 Q5M877
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Top SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Proteine auf antikoerper-online.de

Showing 6 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,684.00
Details

SPSB2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) Interaktionspartnern

Human SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) Interaktionspartner

  1. crystal structure of SPSB2 in complex with cyclic peptide inhibitor cR8 (zeige BHLHE40 Proteine), at a resolution of 1.34 A

Mouse (Murine) SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) Interaktionspartner

  1. Collectively, Ssb1 (zeige SPSB1 Proteine) and Ssb2 control crucial aspects of Hematopoietic stem and progenitor cells function, including proliferation and survival in vivo by resolving replicative stress to maintain genomic stability.

  2. structural changes limit high-affinity interactions for SPSB2 to aspartate-containing sequences

  3. The SPRY domain-containing SOCS (zeige CISH Proteine) box protein SPSB2 targets iNOS (zeige NOS2 Proteine) for proteasomal degradation.

  4. Genetic deletion of SOCS (zeige CISH Proteine) Box Protein 2 results in a very mild thrombocytopenia.

  5. Determined the first SPRY-domain structure of SSB-2 that adopts a novel fold and contains conserved structural determinants for binding to prostate apoptosis response protein-4 (PAR-4 (zeige PAWR Proteine)).

  6. Backbone dynamics of SSB-2 by means of Modelfree analysis.

  7. The binding site on SSB-2 for the prostate apoptosis response-4 (Par-4 (zeige F2RL3 Proteine)) protein has been mapped in finer detail using mutational analyses.

SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) Protein Überblick

Protein Überblick

This gene encodes encodes a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit SPSB2

  • splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2)
  • splA/ryanodine receptor domain and SOCS box containing 2 (Spsb2)
  • AI461677 Protein
  • C9 Protein
  • Grcc9 Protein
  • SSB2 Protein

Bezeichner auf Proteinebene für SPSB2

SPRY domain-containing SOCS box protein 2 , SPRY domain-containing SOCS box protein SSB-2 , gene-rich cluster protein C9 , SSB-2 , gene rich cluster, C9 , gene rich cluster, C9 gene protein

GENE ID SPEZIES
84727 Homo sapiens
14794 Mus musculus
297592 Rattus norvegicus
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